Skin Disorders Diseases Genital Candidiasis

Genital Candidiasis

Genital Candidiasis

Candidiasis, also known as a “yeast infection” or VVC, is a common fungal infection that occurs when there is overgrowth of the fungus called Candida

Genital candidiasis is a Candida infection of the mucosa (nonkeratinized epithelium) of the vulva, vagina, and preputial sac of the penis. Infection usually represents overgrowth of colonizing infection rather than arising from exogenous source.

Causes of Genital Candidiasis

Nearly 75% of all adult women have had at least one genital “yeast infection” in their lifetime. On rare occasions, men may also experience genital candidiasis. VVC occurs more frequently and more severely in people with weakened immune systems.

Symptoms of Genital Candidiasis

Women with VVC usually experience genital itching or burning, with or without a “cottage cheese-like” vaginal discharge. Males with genital candidiasis may experience an itchy rash on the penis.

Diagnosis

Clinical suspicion confirmed by KOH preparation of scraping from mucosal surface.

Treatment

VC/VVC Topical Therapy Azoles/imidazoles are more effective than nystatin and result in relief of symptoms and negative cultures among 80 to 90% of patients after therapy is completed.

Recommended Regimens Single-dose regimens probably should be reserved for cases of uncomplicated mild to moderate VVC. Multiday regimens (3- to 7-day) are the preferred treatment for severe or complicated VVC.

References

  1. https://www.webmd.com/skin-problems-and-treatments/guide/what-is-candidiasis-yeast-infection#1
  2. https://www.sciencedirect.com/science/article/pii/S1357303914001078
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594690/

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